个人简介
东华大学特聘研究员,博士生导师,2017年于日本筑波大学获得博士学位,2017年至2020年于新加坡南洋理工大学从事博士后研究。目前主要从事纳米医学领域的研究,主要集中在设计制备多功能无机、有机纳米材料并探索其在疾病诊断、治疗、药物释放、干细胞调控以及组织工程等方面的潜在应用。迄今在国际知名期刊上发表SCI收录论文120余篇,其中第一作者/通讯作者论文58篇,包括Nat. Commun.、Chem. Soc. Rev.、J. Am. Chem. Soc.、Adv. Mater.、Angew. Chem. Int. Ed.、 Prog. Mater. Sci.、ACS Nano、Biomaterials、Acc. Chem. Res.、ACS Appl. Mater. Interfaces、Adv. Healthcare Mater.、Nano Res.、Nanoscale等,论文总引用次数9300余次,h指数为51。
研究方向
1. 可激活多模态探针的构建用于生物标记物检测和疾病早期诊断;
2. 近红外光响应型纳米调节器的开发与光调控应用;
3. 多功能有机/无机纳米颗粒的构建及其肿瘤等疾病多模态治疗应用;
4. 可注射水凝胶的制备用于细胞功能的调控和组织损伤修复。
荣誉及获奖情况
1. 2020年上海市高校特聘教授(东方学者);
2. 2020年上海市海外高层次人才;
3. 2016年上海市研究生优秀成果奖;
4. 2014年上海市优秀毕业生。
主持与承担主要项目情况
1.上海市教委,上海高校特聘教授(东方学者)支持计划,智能生物纳米技术,2020-9至2023-08,项目主持人,在研。
2. 上海市科学技术委员会,面上项目,双靶向仿生复合纳米颗粒的构建及其骨转移瘤多模态诊疗应用,2022-04至2025-03,项目主持人,在研。
3. 中央高校基本科研业务费学科交叉重点计划项目,肿瘤微环境响应性纳米平台的构建用于脑胶质瘤诊疗研究,2021-01至2023-12,项目主持人,在研。
4. 东华大学高层次人才项目专项基金,有机/无机杂化纳米平台的构建及其肿瘤诊疗应用,2020-9至2023-08,项目主持人,在研。
主要学术论文
1.Jingchao Li#, Yu Luo#, Ziling Zeng, Dong Cui, Jiaguo Huang, Chenjie Xu, Liping Li, Kanyi Pu*, Ruiping Zhang*. Precision cancer sono-immunotherapy using deep-tissue activatable semiconducting polymer immunomodulatory nanoparticles. Nature Communications, 2022, 13, 4032.
2. Ningyue Yu, Linzhou Zhao, Danling Cheng, Mengbin Ding, Yan Lyu, Jinhua Zhao*, Jingchao Li*, Radioactive organic semiconducting polymer nanoparticles for multimodal cancer theranostics, Journal of Colloid and Interface Science, 2022, 619, 219-228.
3. Jingchao Li, Xiangrong Yu, Yuyan Jiang, Shasha He, Yan Zhang*, Yu Luo*, Kanyi Pu*. Second near-infrared photothermal semiconducting polymer nanoadjuvant for enhanced cancer immunotherapy. Advanced Materials, 2021, 33(4), 2003458.
4. Jingchao Li, Yu Luo*, Kanyi Pu*. Electromagnetic nanomedicines for combinational cancer immunotherapy. Angewandte Chemie International Edition, 2021, 60, 12682-12705.
5. Jingchao Li, Kanyi Pu*. Semiconducting polymer nanomaterials as near-infrared photoactivatable protherapeutics for cancer. Accounts of Chemical Research, 2020, 53, 4, 752-762.
6. Jingchao Li, Dong Cui, Yuyan Jiang, Jiaguo Huang, Penghui Cheng, Kanyi Pu*. Near-infrared photoactivatable semiconducting polymer nanoblockaders for metastasis-inhibited combination cancer therapy. Advanced Materials, 2019, 31, 1905091.
7. Jingchao Li, Dong Cui, Jiaguo Huang, Shasha He, Zebin Yang, Yan Zhang*, Yu Luo*, Kanyi Pu*. Organic semiconducting pro-nanostimulants for near-infrared photoactivatable cancer immunotherapy. Angewandte Chemie International Edition, 2019, 58, 12680-12687.
8. Jingchao Li, Hongwei Duan, Kanyi Pu*. Nanotransducers for near-infrared photoregulation in biomedicine. Advanced Materials, 2019, 31, 1901607.
9. Jingchao Li, Jiaguo Huang, Yan Lyu, Jingsheng Huang, Yuyan Jiang, Chen Xie, Kanyi Pu*. Photoactivatable organic semiconducting pro-nanoenzymes. Journal of the American Chemical Society, 2019, 141, 4073-4079.
10. Jingchao Li, Kanyi Pu*. Development of organic semiconducting materials for deep-tissue optical imaging, phototherapy and photoactivation. Chemical Society Reviews, 2019, 48, 38-71.
11. Jingchao Li, Chen Xie, Jiaguo Huang, Yuyan Jiang, Qingqing Miao, and Kanyi Pu*. Semiconducting polymer nanoenzymes with photothermic activity for enhanced cancer therapy. Angewandte Chemie International Edition, 2018, 57, 3995–3998.
12. Jingchao Li, Xu Zhen, Yan Lyu, Yuyan Jiang, Jiaguo Huang, Kanyi Pu*. Cell-membrane coated semiconducting polymer nanoparticles for enhanced multimodal cancer phototheranostics. ACS Nano, 2018, 12, 8520-8530.
其他信息
本课题组招收生物学、化学、材料学、医学等背景硕士/博士研究生,感兴趣者请联系李老师(邮箱jcli@dhu.edu.cn)
联系方式
邮箱:jcli@dhu.edu.cn; 办公室电话:021-67792105。